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Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition
The mechanistic/mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates cellular signals from the nutrient and energy status to act, namely, on the protein synthesis machinery. While major advances have emerged regarding the regulators and effects of the mTOR sign...
Autores principales: | Marques-Ramos, Ana, Candeias, Marco M., Menezes, Juliane, Lacerda, Rafaela, Willcocks, Margaret, Teixeira, Alexandre, Locker, Nicolas, Romão, Luísa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648038/ https://www.ncbi.nlm.nih.gov/pubmed/28821580 http://dx.doi.org/10.1261/rna.063040.117 |
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