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Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial

AIMS: To examine whether physical activity as an adjunct to outpatient alcohol treatment has an effect on alcohol consumption following participation in an exercise intervention of six months’ duration, and at 12 months after treatment initiation. METHODS: The study is a randomized controlled study...

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Autores principales: Roessler, Kirsten K., Bilberg, Randi, Søgaard Nielsen, Anette, Jensen, Kurt, Ekstrøm, Claus Thorn, Sari, Sengül
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648142/
https://www.ncbi.nlm.nih.gov/pubmed/29049336
http://dx.doi.org/10.1371/journal.pone.0186076
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author Roessler, Kirsten K.
Bilberg, Randi
Søgaard Nielsen, Anette
Jensen, Kurt
Ekstrøm, Claus Thorn
Sari, Sengül
author_facet Roessler, Kirsten K.
Bilberg, Randi
Søgaard Nielsen, Anette
Jensen, Kurt
Ekstrøm, Claus Thorn
Sari, Sengül
author_sort Roessler, Kirsten K.
collection PubMed
description AIMS: To examine whether physical activity as an adjunct to outpatient alcohol treatment has an effect on alcohol consumption following participation in an exercise intervention of six months’ duration, and at 12 months after treatment initiation. METHODS: The study is a randomized controlled study with three arms: Patients allocated to (A) treatment as usual, (B) treatment as usual and supervised group exercise, (C) treatment as usual and individual physical exercise. The primary outcome measure was excessive drinking six months after treatment start and completion of the intervention. A logistic regression model was used to evaluate the odds of excessive drinking among the three groups, based on intention-to-treat. Changes in level of physical activity in all three groups were tested by using a generalized linear mixed model. A multiple linear model was used to test if there was an association between amount of performed physical activity and alcohol consumption. RESULTS: A total of 175 patients (68.6% male) participated. Response rates were 77.7% at six months and 57.1% at 12 months follow-up. OR 0.99 [95% CI: 0.46; 2.14], p = 0.976 for excessive drinking in the group exercise condition, and 1.02 [95% CI: 0.47; 2.18], p = 0.968 in the individual exercise condition, which, when compared to the control group as reference, did not differ statistically significantly. Participants with moderate level physical activity had lower odds for excessive drinking OR = 0.12 [0.05; 0.31], p<0.001 than participants with low level physical activity. Amount of alcohol consumption in the intervention groups decreased by 4% [95% CI: 0.03; 6.8], p = 0.015 for each increased exercising day. CONCLUSIONS: No direct effect of physical exercise on drinking outcome was found. Moderate level physical activity was protective against excessive drinking following treatment. A dose-response effect of exercise on drinking outcome supports the need for implementing physically active lifestyles for patients in treatment for alcohol use disorder.
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spelling pubmed-56481422017-11-03 Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial Roessler, Kirsten K. Bilberg, Randi Søgaard Nielsen, Anette Jensen, Kurt Ekstrøm, Claus Thorn Sari, Sengül PLoS One Research Article AIMS: To examine whether physical activity as an adjunct to outpatient alcohol treatment has an effect on alcohol consumption following participation in an exercise intervention of six months’ duration, and at 12 months after treatment initiation. METHODS: The study is a randomized controlled study with three arms: Patients allocated to (A) treatment as usual, (B) treatment as usual and supervised group exercise, (C) treatment as usual and individual physical exercise. The primary outcome measure was excessive drinking six months after treatment start and completion of the intervention. A logistic regression model was used to evaluate the odds of excessive drinking among the three groups, based on intention-to-treat. Changes in level of physical activity in all three groups were tested by using a generalized linear mixed model. A multiple linear model was used to test if there was an association between amount of performed physical activity and alcohol consumption. RESULTS: A total of 175 patients (68.6% male) participated. Response rates were 77.7% at six months and 57.1% at 12 months follow-up. OR 0.99 [95% CI: 0.46; 2.14], p = 0.976 for excessive drinking in the group exercise condition, and 1.02 [95% CI: 0.47; 2.18], p = 0.968 in the individual exercise condition, which, when compared to the control group as reference, did not differ statistically significantly. Participants with moderate level physical activity had lower odds for excessive drinking OR = 0.12 [0.05; 0.31], p<0.001 than participants with low level physical activity. Amount of alcohol consumption in the intervention groups decreased by 4% [95% CI: 0.03; 6.8], p = 0.015 for each increased exercising day. CONCLUSIONS: No direct effect of physical exercise on drinking outcome was found. Moderate level physical activity was protective against excessive drinking following treatment. A dose-response effect of exercise on drinking outcome supports the need for implementing physically active lifestyles for patients in treatment for alcohol use disorder. Public Library of Science 2017-10-19 /pmc/articles/PMC5648142/ /pubmed/29049336 http://dx.doi.org/10.1371/journal.pone.0186076 Text en © 2017 Roessler et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Roessler, Kirsten K.
Bilberg, Randi
Søgaard Nielsen, Anette
Jensen, Kurt
Ekstrøm, Claus Thorn
Sari, Sengül
Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial
title Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial
title_full Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial
title_fullStr Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial
title_full_unstemmed Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial
title_short Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial
title_sort exercise as adjunctive treatment for alcohol use disorder: a randomized controlled trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648142/
https://www.ncbi.nlm.nih.gov/pubmed/29049336
http://dx.doi.org/10.1371/journal.pone.0186076
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