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Spoligotyping and whole-genome sequencing analysis of lineage 1 strains of Mycobacterium tuberculosis in Da Nang, Vietnam

BACKGROUND: Spacer oligonucleotide typing (spoligotyping), a widely used, classical genotyping method for Mycobacterium tuberculosis complex (MTBC), is a PCR-based dot-blot hybridization technique to detect the genetic diversity of the direct repeat (DR) region. Of the seven major MTBC lineages in t...

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Detalles Bibliográficos
Autores principales:	Hijikata, Minako, Keicho, Naoto, Duc, Le Van, Maeda, Shinji, Hang, Nguyen Thi Le, Matsushita, Ikumi, Kato, Seiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648229/ https://www.ncbi.nlm.nih.gov/pubmed/29049400 http://dx.doi.org/10.1371/journal.pone.0186800

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