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Characterization of the catalytic center of the Ebola virus L polymerase

BACKGROUND: Ebola virus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates. While no licensed therapeutics are available, recently there has been tremendous progress in developing antivirals. Targeting the ribonucleoprotein complex (RNP) proteins, which facilitate genome repli...

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Detalles Bibliográficos
Autores principales: Schmidt, Marie Luisa, Hoenen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648267/
https://www.ncbi.nlm.nih.gov/pubmed/28991917
http://dx.doi.org/10.1371/journal.pntd.0005996

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