Cargando…
Characterization of the catalytic center of the Ebola virus L polymerase
BACKGROUND: Ebola virus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates. While no licensed therapeutics are available, recently there has been tremendous progress in developing antivirals. Targeting the ribonucleoprotein complex (RNP) proteins, which facilitate genome repli...
Autores principales: | Schmidt, Marie Luisa, Hoenen, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648267/ https://www.ncbi.nlm.nih.gov/pubmed/28991917 http://dx.doi.org/10.1371/journal.pntd.0005996 |
Ejemplares similares
-
An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication
por: Shabman, Reed S., et al.
Publicado: (2013) -
The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression
por: Wendt, Lisa, et al.
Publicado: (2020) -
Ebola Virus Glycoprotein Domains Associated with Protective Efficacy
por: Bhatia, Bharti, et al.
Publicado: (2021) -
Differences in Viral RNA Synthesis but Not Budding or Entry Contribute to the In Vitro Attenuation of Reston Virus Compared to Ebola Virus
por: Bodmer, Bianca S., et al.
Publicado: (2020) -
Assessment of Life Cycle Modeling Systems as Prediction Tools for a Possible Attenuation of Recombinant Ebola Viruses
por: Bodmer, Bianca S., et al.
Publicado: (2022)