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Adeno-associated virus-mediated neuroglobin overexpression ameliorates the N-methyl-N-nitrosourea-induced retinal impairments: a novel therapeutic strategy against photoreceptor degeneration
Retinal degeneration (RD) is a heterogeneous group of inherited dystrophies leading to blindness. The N-methyl-N-nitrosourea (MNU)-administered mouse is used as a pharmacologically induced RD animal model in various therapeutic investigations. The present study found the retinal neuroglobin (NGB) ex...
Autores principales: | Tao, Ye, Yang, Zhen, Fang, Wei, Ma, Zhao, Huang, Yi Fei, Li, Zhengwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648317/ https://www.ncbi.nlm.nih.gov/pubmed/29075122 http://dx.doi.org/10.2147/TCRM.S144822 |
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