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Hypermethylation in the promoter of the MTHFR gene is associated with diabetic complications and biochemical indicators

BACKGROUND: DNA methylation is an epigenetic mechanism for regulating the transcription of many genes and has been linked to the development of various diseases. A promising gene to investigate is methylenetetrahydrofolate reductase (MTHFR), since the enzyme methylenetetrahydrofolate reductase (MTHF...

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Detalles Bibliográficos
Autores principales:	dos Santos Nunes, Mayara Karla, Silva, Alexandre Sérgio, de Queiroga Evangelista, Isabella Wanderley, Filho, João Modesto, Gomes, Cecília Neta Alves Pegado, do Nascimento, Rayner Anderson Ferreira, Luna, Rafaella Cristhine Pordeus, de Carvalho Costa, Maria José, de Oliveira, Naila Francis Paulo, Persuhn, Darlene Camati
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648437/ https://www.ncbi.nlm.nih.gov/pubmed/29075332 http://dx.doi.org/10.1186/s13098-017-0284-3

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