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Roles of BCCIP deficiency in mammary tumorigenesis

BACKGROUND: Dysregulated DNA repair and cell proliferation controls are essential driving forces in mammary tumorigenesis. BCCIP was originally identified as a BRCA2 and CDKN1A interacting protein that has been implicated in maintenance of genomic stability, cell cycle regulation, and microtubule dy...

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Detalles Bibliográficos
Autores principales: Droz-Rosario, Roberto, Lu, Huimei, Liu, Jingmei, Liu, Ning-Ang, Ganesan, Shridar, Xia, Bing, Haffty, Bruce G., Shen, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648485/
https://www.ncbi.nlm.nih.gov/pubmed/29047390
http://dx.doi.org/10.1186/s13058-017-0907-5