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It is time for top-down venomics

The protein composition of animal venoms is usually determined by peptide-centric proteomics approaches (bottom-up proteomics). However, this technique cannot, in most cases, distinguish among toxin proteoforms, herein called toxiforms, because of the protein inference problem. Top-down proteomics (...

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Detalles Bibliográficos
Autores principales: Melani, Rafael D., Nogueira, Fabio C. S., Domont, Gilberto B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648493/
https://www.ncbi.nlm.nih.gov/pubmed/29075288
http://dx.doi.org/10.1186/s40409-017-0135-6