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Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore
BACKGROUND: Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women. METHODS: As part of the G...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648496/ https://www.ncbi.nlm.nih.gov/pubmed/29047402 http://dx.doi.org/10.1186/s12884-017-1537-8 |
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author | Padmapriya, Natarajan Bernard, Jonathan Y. Liang, Shen Loy, See Ling Cai, Shirong Zhe, Iris Shen Kwek, Kenneth Godfrey, Keith M. Gluckman, Peter D. Saw, Seang Mei Chong, Yap-Seng Chan, Jerry Kok Yen Müller-Riemenschneider, Falk |
author_facet | Padmapriya, Natarajan Bernard, Jonathan Y. Liang, Shen Loy, See Ling Cai, Shirong Zhe, Iris Shen Kwek, Kenneth Godfrey, Keith M. Gluckman, Peter D. Saw, Seang Mei Chong, Yap-Seng Chan, Jerry Kok Yen Müller-Riemenschneider, Falk |
author_sort | Padmapriya, Natarajan |
collection | PubMed |
description | BACKGROUND: Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women. METHODS: As part of the Growing Up in Singapore Towards healthy Outcomes cohort study, PA and SB (sitting and television times) were assessed by interviewer-administered questionnaire. During 75 g oral glucose tolerance tests at 26–28 weeks’ gestation we measured FG, 2hPG levels and GDM (FG ≥ 7.0 mmol/L and/or 2hPG ≥ 7.8 mmol/L). Associations were analysed by multiple linear and logistic regression. RESULTS: Among the 1083 women studied, 18.6% had GDM. SB was not associated with FG, 2hPG and GDM. Higher categories of PA were associated with lower 2hPG and a lower likelihood of GDM (p-trend < 0.05), but not with FG levels. Compared to insufficiently active women, highly active women had lower 2hPG levels [β (95% CI): -0.32 (−0.59, −0.05), p = 0.020) and were less likely to have GDM [OR: 0.56 (0.32–0.98), p = 0.040]. Stratified analysis revealed no associations among under/normal-weight women, but significant associations among overweight/obese women; in those with BMI ≥23 kg/m(2), sufficiently active and highly active women were less likely to have GDM [OR: 0.52, (0.29–0.93), p = 0.028, and OR: 0.34, (0.15–0.77), p = 0.010, respectively]. CONCLUSION: Higher PA was associated with lower 2hPG levels and a lower prevalence of GDM, particularly in overweight/obese women. Further studies are warranted to confirm these findings, and to examine the effectiveness of PA promotion strategies for the prevention of gestational hyperglycemia. |
format | Online Article Text |
id | pubmed-5648496 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-56484962017-10-26 Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore Padmapriya, Natarajan Bernard, Jonathan Y. Liang, Shen Loy, See Ling Cai, Shirong Zhe, Iris Shen Kwek, Kenneth Godfrey, Keith M. Gluckman, Peter D. Saw, Seang Mei Chong, Yap-Seng Chan, Jerry Kok Yen Müller-Riemenschneider, Falk BMC Pregnancy Childbirth Research Article BACKGROUND: Few studies have investigated physical activity (PA) and sedentary behavior (SB) in relation to fasting (FG) and 2-h postprandial plasma glucose (2hPG) levels and gestational diabetes mellitus (GDM); we investigated these associations among Asian pregnant women. METHODS: As part of the Growing Up in Singapore Towards healthy Outcomes cohort study, PA and SB (sitting and television times) were assessed by interviewer-administered questionnaire. During 75 g oral glucose tolerance tests at 26–28 weeks’ gestation we measured FG, 2hPG levels and GDM (FG ≥ 7.0 mmol/L and/or 2hPG ≥ 7.8 mmol/L). Associations were analysed by multiple linear and logistic regression. RESULTS: Among the 1083 women studied, 18.6% had GDM. SB was not associated with FG, 2hPG and GDM. Higher categories of PA were associated with lower 2hPG and a lower likelihood of GDM (p-trend < 0.05), but not with FG levels. Compared to insufficiently active women, highly active women had lower 2hPG levels [β (95% CI): -0.32 (−0.59, −0.05), p = 0.020) and were less likely to have GDM [OR: 0.56 (0.32–0.98), p = 0.040]. Stratified analysis revealed no associations among under/normal-weight women, but significant associations among overweight/obese women; in those with BMI ≥23 kg/m(2), sufficiently active and highly active women were less likely to have GDM [OR: 0.52, (0.29–0.93), p = 0.028, and OR: 0.34, (0.15–0.77), p = 0.010, respectively]. CONCLUSION: Higher PA was associated with lower 2hPG levels and a lower prevalence of GDM, particularly in overweight/obese women. Further studies are warranted to confirm these findings, and to examine the effectiveness of PA promotion strategies for the prevention of gestational hyperglycemia. BioMed Central 2017-10-18 /pmc/articles/PMC5648496/ /pubmed/29047402 http://dx.doi.org/10.1186/s12884-017-1537-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Padmapriya, Natarajan Bernard, Jonathan Y. Liang, Shen Loy, See Ling Cai, Shirong Zhe, Iris Shen Kwek, Kenneth Godfrey, Keith M. Gluckman, Peter D. Saw, Seang Mei Chong, Yap-Seng Chan, Jerry Kok Yen Müller-Riemenschneider, Falk Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
title | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
title_full | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
title_fullStr | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
title_full_unstemmed | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
title_short | Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore |
title_sort | associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among asian women in singapore |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648496/ https://www.ncbi.nlm.nih.gov/pubmed/29047402 http://dx.doi.org/10.1186/s12884-017-1537-8 |
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