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Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models
BACKGROUND: Thymosin β4 (Tβ4) is closely associated with the cytoskeleton, inflammation, wound healing, angiogenesis, apoptosis, and myocardial regeneration, but the effects of Tβ4 treatment on chronic renal tubular interstitial fibrosis (CRTIF) are poorly known. This study aimed to examine the effe...
Autores principales: | Yuan, Jing, Shen, Yan, Yang, Xia, Xie, Ying, Lin, Xin, Zeng, Wen, Zhao, Yingting, Tian, Maolu, Zha, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648500/ https://www.ncbi.nlm.nih.gov/pubmed/29047363 http://dx.doi.org/10.1186/s12882-017-0708-1 |
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