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Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila

Our understanding of the molecular mechanisms underlying sleep homeostasis is limited. We have taken a systematic approach to study neural signaling by the transmitter 5-hydroxytryptamine (5-HT) in drosophila. We have generated knockout and knockin lines for Trh, the 5-HT synthesizing enzyme and all...

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Detalles Bibliográficos
Autores principales: Qian, Yongjun, Cao, Yue, Deng, Bowen, Yang, Guang, Li, Jiayun, Xu, Rui, zhang, Dandan, Huang, Juan, Rao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648528/
https://www.ncbi.nlm.nih.gov/pubmed/28984573
http://dx.doi.org/10.7554/eLife.26519