Cargando…

YTHDC1 mediates nuclear export of N(6)-methyladenosine methylated mRNAs

N(6)-methyladenosine (m(6)A) is the most abundant internal modification of eukaryotic messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this modification is mediated by m(6)A-selective ‘reader’ proteins of the YTH family, which incorporate m(6)A-modified mRNAs into pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roundtree, Ian A, Luo, Guan-Zheng, Zhang, Zijie, Wang, Xiao, Zhou, Tao, Cui, Yiquang, Sha, Jiahao, Huang, Xingxu, Guerrero, Laura, Xie, Phil, He, Emily, Shen, Bin, He, Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648532/ https://www.ncbi.nlm.nih.gov/pubmed/28984244 http://dx.doi.org/10.7554/eLife.31311

Ejemplares similares

Polyadenylation and nuclear export of mRNAs
por: Stewart, Murray
Publicado: (2019)

Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells
por: Park, Seongjin, et al.
Publicado: (2021)

Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity
por: Yourik, Paul, et al.
Publicado: (2017)

Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals
por: Li, Yuling, et al.
Publicado: (2019)

Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition
por: Alghoul, Fatima, et al.
Publicado: (2021)

MicroRNA-mediated repression of nonsense mRNAs
por: Zhao, Ya, et al.
Publicado: (2014)

FMRP Regulates the Nuclear Export of Adam9 and Psen1 mRNAs: Secondary Analysis of an N(6)-Methyladenosine Dataset
por: Westmark, Cara J., et al.
Publicado: (2020)

RNA-guided assembly of Rev-RRE nuclear export complexes
por: Bai, Yun, et al.
Publicado: (2014)

Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1
por: Trinh, Michael Nguyen, et al.
Publicado: (2018)

Sequence Determinants for Nuclear Retention and Cytoplasmic Export of mRNAs and lncRNAs
por: Palazzo, Alexander F., et al.
Publicado: (2018)

LTA4H extensively associates with mRNAs and lncRNAs indicative of its novel regulatory targets
por: Ren, Tianjiao, et al.
Publicado: (2023)

Structural determinants of nuclear export signal orientation in binding to exportin CRM1
por: Fung, Ho Yee Joyce, et al.
Publicado: (2015)

Transcription analyses of differentially expressed mRNAs, lncRNAs, circRNAs, and miRNAs in the growth plate of rats with glucocorticoid-induced growth retardation
por: Yin, Mingyue, et al.
Publicado: (2023)

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
por: Kırlı, Koray, et al.
Publicado: (2015)

Multiple Export Mechanisms for mRNAs
por: Delaleau, Mildred, et al.
Publicado: (2015)

The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs
por: Thompson, Mary K, et al.
Publicado: (2016)

Registered report: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
por: Khan, Israr, et al.
Publicado: (2015)

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs
por: Zhou, Hao, et al.
Publicado: (2017)

Intronless mRNAs transit through nuclear speckles to gain export competence
por: Wang, Ke, et al.
Publicado: (2018)

mRNAs are sorted for export or degradation before passing through nuclear speckles
por: Fan, Jing, et al.
Publicado: (2018)

N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast
por: Varier, Radhika A, et al.
Publicado: (2022)

Correction: Registered report: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
por: Khan, Israr, et al.
Publicado: (2015)

Correction: Registered report: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
por: Khan, Israr, et al.
Publicado: (2015)

Our views of dynamic N(6)-methyladenosine RNA methylation
por: Zhao, Boxuan Simen, et al.
Publicado: (2018)

LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs
por: Hong, Sungki, et al.
Publicado: (2017)

Nuclear m6A reader YTHDC1 promotes muscle stem cell activation/proliferation by regulating mRNA splicing and nuclear export
por: Qiao, Yulong, et al.
Publicado: (2023)

Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway
por: Ge, Zhiyun, et al.
Publicado: (2016)

Influenza polymerase encoding mRNAs utilize atypical mRNA nuclear export
por: Larsen, Sean, et al.
Publicado: (2014)

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs
por: Lahr, Roni M, et al.
Publicado: (2017)

RNA sequencing reveals novel LncRNA/mRNAs co-expression network associated with puerarin-mediated inhibition of cardiac hypertrophy in mice
por: Ye, Shan, et al.
Publicado: (2022)

eIF4E exports proliferation mRNAs
por: LeBrasseur, Nicole
Publicado: (2006)

A Method for Measuring RNA N(6)-methyladenosine Modifications in Cells and Tissues
por: Wang, Chao-Yung, et al.
Publicado: (2016)

TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes
por: Lee, Eliza S, et al.
Publicado: (2020)

SON and SRRM2 are essential for nuclear speckle formation
por: Ilik, İbrahim Avşar, et al.
Publicado: (2020)

N(6)-methyladenosine is required for the hypoxic stabilization of specific mRNAs
por: Fry, Nate J., et al.
Publicado: (2017)

Analysis of N6-methyladenosine-modified mRNAs in diabetic cataract
por: Cai, Lei, et al.
Publicado: (2023)

Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers
por: Limi, Saima, et al.
Publicado: (2019)

Distinct and evolutionary conserved structural features of the human nuclear exosome complex
por: Gerlach, Piotr, et al.
Publicado: (2018)

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
por: Shang, Jinsai, et al.
Publicado: (2018)

YTHDC2-Mediated circYTHDC2 N6-Methyladenosine Modification Promotes Vascular Smooth Muscle Cells Dysfunction Through Inhibiting Ten-Eleven Translocation 2
por: Yuan, Jun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_higpbdkp8c23eh9fkc4olrc80c