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The giant protein titin regulates the length of the striated muscle thick filament

The contractile machinery of heart and skeletal muscles has as an essential component the thick filament, comprised of the molecular motor myosin. The thick filament is of a precisely controlled length, defining thereby the force level that muscles generate and how this force varies with muscle leng...

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Detalles Bibliográficos
Autores principales:	Tonino, Paola, Kiss, Balazs, Strom, Josh, Methawasin, Mei, Smith, John E., Kolb, Justin, Labeit, Siegfried, Granzier, Henk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648799/ https://www.ncbi.nlm.nih.gov/pubmed/29051486 http://dx.doi.org/10.1038/s41467-017-01144-9

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