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The efficacy and further functional advantages of random-base molecular barcodes for absolute and digital quantification of nucleic acid molecules

Accurate quantification of biomolecules in system-wide measurements is in high demand, especially for systems with limited sample amounts such as single cells. Because of this, digital quantification of nucleic acid molecules using molecular barcodes has been developed, making, e.g., transcriptome a...

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Detalles Bibliográficos
Autores principales: Ogawa, Taisaku, Kryukov, Kirill, Imanishi, Tadashi, Shiroguchi, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648891/
https://www.ncbi.nlm.nih.gov/pubmed/29051542
http://dx.doi.org/10.1038/s41598-017-13529-3