DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice

Retrotransposon long interspersed nuclear element-1 (LINE-1) occupies a large proportion of the mammalian genome, comprising approximately 100,000 genomic copies in mice. Epigenetic status of the 5′ untranslated region (5′-UTR) of LINE-1 is critical for its promoter activity. DNA methylation levels...

Descripción completa

Detalles Bibliográficos
Autores principales: Murata, Yui, Bundo, Miki, Ueda, Junko, Kubota-Sakashita, Mie, Kasai, Kiyoto, Kato, Tadafumi, Iwamoto, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648895/
https://www.ncbi.nlm.nih.gov/pubmed/29051587
http://dx.doi.org/10.1038/s41598-017-14165-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648895/
https://www.ncbi.nlm.nih.gov/pubmed/29051587
http://dx.doi.org/10.1038/s41598-017-14165-7

Ejemplares similares