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DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice

Retrotransposon long interspersed nuclear element-1 (LINE-1) occupies a large proportion of the mammalian genome, comprising approximately 100,000 genomic copies in mice. Epigenetic status of the 5′ untranslated region (5′-UTR) of LINE-1 is critical for its promoter activity. DNA methylation levels...

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Detalles Bibliográficos
Autores principales:	Murata, Yui, Bundo, Miki, Ueda, Junko, Kubota-Sakashita, Mie, Kasai, Kiyoto, Kato, Tadafumi, Iwamoto, Kazuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648895/ https://www.ncbi.nlm.nih.gov/pubmed/29051587 http://dx.doi.org/10.1038/s41598-017-14165-7

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