Spontaneous Loss of Virulence in Natural Populations of Listeria monocytogenes

The pathogenesis of Listeria monocytogenes depends on the ability of this bacterium to escape from the phagosome of the host cells via the action of the pore-forming toxin listeriolysin O (LLO). Expression of the LLO-encoding gene (hly) requires the transcriptional activator PrfA, and both hly and p...

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Detalles Bibliográficos
Autores principales: Maury, Mylène M., Chenal-Francisque, Viviane, Bracq-Dieye, Hélène, Han, Lei, Leclercq, Alexandre, Vales, Guillaume, Moura, Alexandra, Gouin, Edith, Scortti, Mariela, Disson, Olivier, Vázquez-Boland, José A., Lecuit, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Molecular Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649026/
https://www.ncbi.nlm.nih.gov/pubmed/28827366
http://dx.doi.org/10.1128/IAI.00541-17

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