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PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer

BACKGROUND: PTEN (phosphatase and tensin homolog gene on chromosome 10), a well-characterized tumor suppressor, is a key regulator of the phosphatidylinositol-3-kinase (PI3K)/AKT pathway involved in cell survival, metastasis and cell renewal. PTEN expression is closely related to the phenotype, prog...

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Detalles Bibliográficos
Autores principales:	Zhou, Xu-Jie, Wu, Jing, Shi, Liang, Li, Xiao-Xia, Zhu, Lei, Sun, Xi, Qian, Jia-Yi, Wang, Ying, Wei, Ji-Fu, Ding, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649103/ https://www.ncbi.nlm.nih.gov/pubmed/29052531 http://dx.doi.org/10.1186/s13046-017-0620-3

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