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High-throughput imaging assay of multiple proteins via target-induced DNA assembly and cleavage

This work integrates target-induced DNA assembly and cleavage on a DNA chip to design a versatile imaging strategy as an assay for multiple proteins. The DNA assembly is achieved via immunological recognition to trigger the proximity hybridization for releasing a DNA sequence, which then hybridizes...

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Detalles Bibliográficos
Autores principales: Zong, Chen, Wu, Jie, Liu, Mengmeng, Yan, Feng, Ju, Huangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649240/
https://www.ncbi.nlm.nih.gov/pubmed/29308164
http://dx.doi.org/10.1039/c4sc03809f

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