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Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer

Regulatory T (Treg) cell infiltration constitutes a prominent feature of pancreatic ductal adenocarcinoma (PDA). However, the immunomodulatory function of Treg cells in PDA is poorly understood. Here, we demonstrate that Treg cell ablation is sufficient to evoke effective anti-tumor immune response...

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Detalles Bibliográficos
Autores principales:	Jang, Jung-Eun, Hajdu, Cristina H., Liot, Caroline, Miller, George, Dustin, Michael L., Bar-Sagi, Dafna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649374/ https://www.ncbi.nlm.nih.gov/pubmed/28723561 http://dx.doi.org/10.1016/j.celrep.2017.06.062

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