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Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial
Over the past decade, vectors derived from adeno-associated virus (AAV) have established themselves as a powerful tool for in vivo gene transfer, allowing long-lasting and safe transgene expression in a variety of human tissues. Nevertheless, clinical trials demonstrated how B and T cell immune resp...
Autores principales: | Vandamme, Céline, Adjali, Oumeya, Mingozzi, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649404/ https://www.ncbi.nlm.nih.gov/pubmed/28835127 http://dx.doi.org/10.1089/hum.2017.150 |
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