Ammonia-induced mitochondrial dysfunction and energy metabolism disturbances in isolated brain and liver mitochondria, and the effect of taurine administration: relevance to hepatic encephalopathy treatment

INTRODUCTION: Ammonia-induced oxidative stress, mitochondrial dysfunction, and energy crisis are known as some the major mechanisms of brain injury in hepatic encephalopathy (HE). Hyperammonemia also affects the liver and hepatocytes. Therefore, targeting mitochondria seems to be a therapeutic point...

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Detalles Bibliográficos
Autores principales: Niknahad, Hossein, Jamshidzadeh, Akram, Heidari, Reza, Zarei, Mahdi, Ommati, Mohammad Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649485/
https://www.ncbi.nlm.nih.gov/pubmed/29062904
http://dx.doi.org/10.5114/ceh.2017.68833

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