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The Lethal Spanish Influenza Pandemic in Poland

The Spanish influenza pandemic in the years 1918–1920 was the largest and most tragic pandemic of infectious disease in human history. Deciphering the structure of the virus (including the determination of complete genome sequence) of this pandemic and the phylogenetic analysis and explanation of it...

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Autores principales: Grabowski, Marek L., Kosińska, Bożena, Knap, Józef P., Brydak, Lidia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649514/
https://www.ncbi.nlm.nih.gov/pubmed/29021518
http://dx.doi.org/10.12659/MSM.906280
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author Grabowski, Marek L.
Kosińska, Bożena
Knap, Józef P.
Brydak, Lidia B.
author_facet Grabowski, Marek L.
Kosińska, Bożena
Knap, Józef P.
Brydak, Lidia B.
author_sort Grabowski, Marek L.
collection PubMed
description The Spanish influenza pandemic in the years 1918–1920 was the largest and most tragic pandemic of infectious disease in human history. Deciphering the structure of the virus (including the determination of complete genome sequence) of this pandemic and the phylogenetic analysis and explanation of its virulence became possible thanks to molecular genetic analysis of the virus isolated from the fixed and frozen lung tissue of influenza victims who died in 1918 and were buried frozen in Alaska and Spitsbergen. Epidemiological data from the course of this pandemic in Poland have not been previously published. For analysis, we used source materials such as clinical studies and case reports of doctors fighting against the pandemic and registries of influenza cases in units of the Polish Army and military hospitals. Clinically, the pandemic of 1918 was characterized by the same symptoms and course as influenza in other years. Pathologically, the disease was similar to the other pandemic, in that the destruction was mostly limited to the respiratory tract. The “Spanish” influenza pandemic of 1918–1920 took place in Poland in 3 epidemic waves. The peaks of morbidity and mortality occurred in the capital, Warsaw, in December 1918 and in December 1919 to January 1920. It is estimated that throughout the pandemic period of 1918–1920 in Poland, 200 000 to 300 000 people died.
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spelling pubmed-56495142017-10-26 The Lethal Spanish Influenza Pandemic in Poland Grabowski, Marek L. Kosińska, Bożena Knap, Józef P. Brydak, Lidia B. Med Sci Monit Special Reports The Spanish influenza pandemic in the years 1918–1920 was the largest and most tragic pandemic of infectious disease in human history. Deciphering the structure of the virus (including the determination of complete genome sequence) of this pandemic and the phylogenetic analysis and explanation of its virulence became possible thanks to molecular genetic analysis of the virus isolated from the fixed and frozen lung tissue of influenza victims who died in 1918 and were buried frozen in Alaska and Spitsbergen. Epidemiological data from the course of this pandemic in Poland have not been previously published. For analysis, we used source materials such as clinical studies and case reports of doctors fighting against the pandemic and registries of influenza cases in units of the Polish Army and military hospitals. Clinically, the pandemic of 1918 was characterized by the same symptoms and course as influenza in other years. Pathologically, the disease was similar to the other pandemic, in that the destruction was mostly limited to the respiratory tract. The “Spanish” influenza pandemic of 1918–1920 took place in Poland in 3 epidemic waves. The peaks of morbidity and mortality occurred in the capital, Warsaw, in December 1918 and in December 1919 to January 1920. It is estimated that throughout the pandemic period of 1918–1920 in Poland, 200 000 to 300 000 people died. International Scientific Literature, Inc. 2017-10-12 /pmc/articles/PMC5649514/ /pubmed/29021518 http://dx.doi.org/10.12659/MSM.906280 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Special Reports
Grabowski, Marek L.
Kosińska, Bożena
Knap, Józef P.
Brydak, Lidia B.
The Lethal Spanish Influenza Pandemic in Poland
title The Lethal Spanish Influenza Pandemic in Poland
title_full The Lethal Spanish Influenza Pandemic in Poland
title_fullStr The Lethal Spanish Influenza Pandemic in Poland
title_full_unstemmed The Lethal Spanish Influenza Pandemic in Poland
title_short The Lethal Spanish Influenza Pandemic in Poland
title_sort lethal spanish influenza pandemic in poland
topic Special Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649514/
https://www.ncbi.nlm.nih.gov/pubmed/29021518
http://dx.doi.org/10.12659/MSM.906280
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