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How to normalize metatranscriptomic count data for differential expression analysis
BACKGROUND: Differential expression analysis on the basis of RNA-Seq count data has become a standard tool in transcriptomics. Several studies have shown that prior normalization of the data is crucial for a reliable detection of transcriptional differences. Until now it has not been clear whether a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649605/ https://www.ncbi.nlm.nih.gov/pubmed/29062598 http://dx.doi.org/10.7717/peerj.3859 |