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How to normalize metatranscriptomic count data for differential expression analysis

BACKGROUND: Differential expression analysis on the basis of RNA-Seq count data has become a standard tool in transcriptomics. Several studies have shown that prior normalization of the data is crucial for a reliable detection of transcriptional differences. Until now it has not been clear whether a...

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Detalles Bibliográficos
Autores principales: Klingenberg, Heiner, Meinicke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649605/
https://www.ncbi.nlm.nih.gov/pubmed/29062598
http://dx.doi.org/10.7717/peerj.3859