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HLA-mediated tumor escape mechanisms that may impair immunotherapy clinical outcomes via T-cell activation
Although the immune system provides protection from cancer by means of immunosurveillance, which serves a major function in eliminating cancer cells, it may also lead to cancer immunoediting, molding tumor immunogenicity. Cancer cells exploit several molecular mechanisms to thwart immune-mediated de...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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D.A. Spandidos
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649701/ https://www.ncbi.nlm.nih.gov/pubmed/29085437 http://dx.doi.org/10.3892/ol.2017.6784 |