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Targeting RhoC by Way of Ribozyme Trangene in Human Breast Cancer Cells and its Impact on Cancer Invasion

BACKGROUND: Cell motility and migration are known to be regulated by the Rho family of GTPases through their effects on the actin cytoskeleton. In breast cancer studies, RhoC has been identified as a highly specific marker in detecting tumors that developed metastases. This study aims to investigate...

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Detalles Bibliográficos
Autores principales: Lane, Jane, Martin, Tracey A, Jiang, Wen G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649728/
https://www.ncbi.nlm.nih.gov/pubmed/29147173
http://dx.doi.org/10.4021/wjon2010.01.1202