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(1)H-MRS metabolites and rate of β-amyloid accumulation on serial PET in clinically normal adults

OBJECTIVE: To assess whether noninvasive proton magnetic resonance spectroscopy ((1)H-MRS) tissue metabolite measurements at baseline can predict an increase in the rate of β-amyloid (Aβ) accumulation on serial PET in clinically normal (CN) older adults. METHODS: Consecutive participants aged 60 yea...

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Detalles Bibliográficos
Autores principales:	Nedelska, Zuzana, Przybelski, Scott A., Lesnick, Timothy G., Schwarz, Christopher G., Lowe, Val J., Machulda, Mary M., Kremers, Walter K., Mielke, Michelle M., Roberts, Rosebud O., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Jack, Clifford R., Kantarci, Kejal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649764/ https://www.ncbi.nlm.nih.gov/pubmed/28842444 http://dx.doi.org/10.1212/WNL.0000000000004421

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