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Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metast...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649841/ https://www.ncbi.nlm.nih.gov/pubmed/29147302 http://dx.doi.org/10.4021/wjon481w |
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author | Shirzadi, Ali Drazin, Doniel Shirzadi, Neda Westhout, Franklin Drazin, Noam Fan, Xuemo Acosta, Frank L. |
author_facet | Shirzadi, Ali Drazin, Doniel Shirzadi, Neda Westhout, Franklin Drazin, Noam Fan, Xuemo Acosta, Frank L. |
author_sort | Shirzadi, Ali |
collection | PubMed |
description | Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metastasis to the spine with a previous history of known primary disease complicated by thrombocytopenia. Thrombocytopenia can present surgical challenges, but can also be present concurrently unrelated to the primary disease. A thorough evaluation is needed to rule out any underlying lymphoproliferative disorder or microangiopathic phenomenon. |
format | Online Article Text |
id | pubmed-5649841 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56498412017-11-16 Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia Shirzadi, Ali Drazin, Doniel Shirzadi, Neda Westhout, Franklin Drazin, Noam Fan, Xuemo Acosta, Frank L. World J Oncol Case Report Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metastasis to the spine with a previous history of known primary disease complicated by thrombocytopenia. Thrombocytopenia can present surgical challenges, but can also be present concurrently unrelated to the primary disease. A thorough evaluation is needed to rule out any underlying lymphoproliferative disorder or microangiopathic phenomenon. Elmer Press 2012-08 2012-08-26 /pmc/articles/PMC5649841/ /pubmed/29147302 http://dx.doi.org/10.4021/wjon481w Text en Copyright 2012, Shirzadi et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Shirzadi, Ali Drazin, Doniel Shirzadi, Neda Westhout, Franklin Drazin, Noam Fan, Xuemo Acosta, Frank L. Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia |
title | Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia |
title_full | Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia |
title_fullStr | Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia |
title_full_unstemmed | Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia |
title_short | Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia |
title_sort | metastatic leiomyosarcoma to the spine complicated with thrombocytopenia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649841/ https://www.ncbi.nlm.nih.gov/pubmed/29147302 http://dx.doi.org/10.4021/wjon481w |
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