Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia

Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metast...

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Autores principales: Shirzadi, Ali, Drazin, Doniel, Shirzadi, Neda, Westhout, Franklin, Drazin, Noam, Fan, Xuemo, Acosta, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649841/
https://www.ncbi.nlm.nih.gov/pubmed/29147302
http://dx.doi.org/10.4021/wjon481w
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author Shirzadi, Ali
Drazin, Doniel
Shirzadi, Neda
Westhout, Franklin
Drazin, Noam
Fan, Xuemo
Acosta, Frank L.
author_facet Shirzadi, Ali
Drazin, Doniel
Shirzadi, Neda
Westhout, Franklin
Drazin, Noam
Fan, Xuemo
Acosta, Frank L.
author_sort Shirzadi, Ali
collection PubMed
description Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metastasis to the spine with a previous history of known primary disease complicated by thrombocytopenia. Thrombocytopenia can present surgical challenges, but can also be present concurrently unrelated to the primary disease. A thorough evaluation is needed to rule out any underlying lymphoproliferative disorder or microangiopathic phenomenon.
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spelling pubmed-56498412017-11-16 Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia Shirzadi, Ali Drazin, Doniel Shirzadi, Neda Westhout, Franklin Drazin, Noam Fan, Xuemo Acosta, Frank L. World J Oncol Case Report Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metastasis to the spine with a previous history of known primary disease complicated by thrombocytopenia. Thrombocytopenia can present surgical challenges, but can also be present concurrently unrelated to the primary disease. A thorough evaluation is needed to rule out any underlying lymphoproliferative disorder or microangiopathic phenomenon. Elmer Press 2012-08 2012-08-26 /pmc/articles/PMC5649841/ /pubmed/29147302 http://dx.doi.org/10.4021/wjon481w Text en Copyright 2012, Shirzadi et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shirzadi, Ali
Drazin, Doniel
Shirzadi, Neda
Westhout, Franklin
Drazin, Noam
Fan, Xuemo
Acosta, Frank L.
Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
title Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
title_full Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
title_fullStr Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
title_full_unstemmed Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
title_short Metastatic Leiomyosarcoma to the Spine Complicated With Thrombocytopenia
title_sort metastatic leiomyosarcoma to the spine complicated with thrombocytopenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649841/
https://www.ncbi.nlm.nih.gov/pubmed/29147302
http://dx.doi.org/10.4021/wjon481w
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