Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman

Concurrent acute myeloid leukemia (AML) and multiple myeloma (MM) is rare, more so in chemotherapy-naive patients. Concurrent occurrence of these two malignancies portends poor prognosis. Although anthracycline-based AML regimen, allogeneic hematopoietic stem cell transplantation, tipifarnib and bor...

Descripción completa

Detalles Bibliográficos
Autores principales: Murukutla, Srujitha, Arora, Swaty, Bhatt, Vijaya Raj, Kedia, Shiksha, Popalzai, Muhammad, Dhar, Meekoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649876/
https://www.ncbi.nlm.nih.gov/pubmed/29147380
http://dx.doi.org/10.14740/wjon722w
_version_ 1783272623870836736
author Murukutla, Srujitha
Arora, Swaty
Bhatt, Vijaya Raj
Kedia, Shiksha
Popalzai, Muhammad
Dhar, Meekoo
author_facet Murukutla, Srujitha
Arora, Swaty
Bhatt, Vijaya Raj
Kedia, Shiksha
Popalzai, Muhammad
Dhar, Meekoo
author_sort Murukutla, Srujitha
collection PubMed
description Concurrent acute myeloid leukemia (AML) and multiple myeloma (MM) is rare, more so in chemotherapy-naive patients. Concurrent occurrence of these two malignancies portends poor prognosis. Although anthracycline-based AML regimen, allogeneic hematopoietic stem cell transplantation, tipifarnib and bortezomib have shown promising results in small number of patients, there is a lack of established therapy. We describe a case of concurrent AML and MM in a 66-year-old woman and review previously published literature.
format Online
Article
Text
id pubmed-5649876
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Elmer Press
record_format MEDLINE/PubMed
spelling pubmed-56498762017-11-16 Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman Murukutla, Srujitha Arora, Swaty Bhatt, Vijaya Raj Kedia, Shiksha Popalzai, Muhammad Dhar, Meekoo World J Oncol Case Report Concurrent acute myeloid leukemia (AML) and multiple myeloma (MM) is rare, more so in chemotherapy-naive patients. Concurrent occurrence of these two malignancies portends poor prognosis. Although anthracycline-based AML regimen, allogeneic hematopoietic stem cell transplantation, tipifarnib and bortezomib have shown promising results in small number of patients, there is a lack of established therapy. We describe a case of concurrent AML and MM in a 66-year-old woman and review previously published literature. Elmer Press 2014-04 2014-05-06 /pmc/articles/PMC5649876/ /pubmed/29147380 http://dx.doi.org/10.14740/wjon722w Text en Copyright 2014, Murukutla et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Murukutla, Srujitha
Arora, Swaty
Bhatt, Vijaya Raj
Kedia, Shiksha
Popalzai, Muhammad
Dhar, Meekoo
Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
title Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
title_full Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
title_fullStr Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
title_full_unstemmed Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
title_short Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
title_sort concurrent acute monoblastic leukemia and multiple myeloma in a 66-year-old chemotherapy-naive woman
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649876/
https://www.ncbi.nlm.nih.gov/pubmed/29147380
http://dx.doi.org/10.14740/wjon722w
work_keys_str_mv AT murukutlasrujitha concurrentacutemonoblasticleukemiaandmultiplemyelomaina66yearoldchemotherapynaivewoman
AT aroraswaty concurrentacutemonoblasticleukemiaandmultiplemyelomaina66yearoldchemotherapynaivewoman
AT bhattvijayaraj concurrentacutemonoblasticleukemiaandmultiplemyelomaina66yearoldchemotherapynaivewoman
AT kediashiksha concurrentacutemonoblasticleukemiaandmultiplemyelomaina66yearoldchemotherapynaivewoman
AT popalzaimuhammad concurrentacutemonoblasticleukemiaandmultiplemyelomaina66yearoldchemotherapynaivewoman
AT dharmeekoo concurrentacutemonoblasticleukemiaandmultiplemyelomaina66yearoldchemotherapynaivewoman

Ejemplares similares