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Phytosphingosine exhibits an anti-epithelial–mesenchymal transition function by the inhibition of EGFR signaling in human breast cancer cells

The lack of effective anti-metastatic drugs for the eradication of breast cancer stem cells within tumors, which are often resistant to chemotherapy and radiotherapy, creates a major obstacle during metastatic breast cancer therapy. Although D-ribo-phytosphingosine (PHS) is well known to activate pr...

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Detalles Bibliográficos
Autores principales: Kang, Hye-Min, Son, Han-Sun, Cui, Yan-Hong, Youn, BuHyun, Son, Beomseok, Kaushik, Nagendra Kumar, Uddin, Nizam, Lee, Jae-Seong, Song, Jie-Young, Kaushik, Neha, Lee, Su-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649924/
https://www.ncbi.nlm.nih.gov/pubmed/29100426
http://dx.doi.org/10.18632/oncotarget.20783