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High glucose augments angiotensinogen in human renal proximal tubular cells through hepatocyte nuclear factor-5

High glucose has been demonstrated to induce angiotensinogen (AGT) synthesis in the renal proximal tubular cells (RPTCs) of rats, which may further activate the intrarenal renin-angiotensin system (RAS) and contribute to diabetic nephropathy. This study aimed to investigate the effects of high gluco...

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Detalles Bibliográficos
Autores principales:	Wang, Juan, Shibayama, Yuki, Kobori, Hiroyuki, Liu, Ya, Kobara, Hideki, Masaki, Tsutomu, Wang, Zhiyu, Nishiyama, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650141/ https://www.ncbi.nlm.nih.gov/pubmed/29053707 http://dx.doi.org/10.1371/journal.pone.0185600

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