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Novel calpain families and novel mechanisms for calpain regulation in Aplysia

Calpains are a family of intracellular proteases defined by a conserved protease domain. In the marine mollusk Aplysia californica, calpains are important for the induction of long-term synaptic plasticity and memory, at least in part by cleaving protein kinase Cs (PKCs) into constitutively active k...

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Detalles Bibliográficos
Autores principales: Hastings, Margaret H., Gong, Katrina, Freibauer, Alexander, Courchesne, Caitlin, Fan, Xiaotang, Sossin, Wayne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650170/
https://www.ncbi.nlm.nih.gov/pubmed/29053733
http://dx.doi.org/10.1371/journal.pone.0186646