Cargando…
Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis
Lysine-specific demethylase 1 (LSD1) is a nuclear histone demethylase and a member of the amine oxidase (AO) family. LSD1 is a flavin-containing AO that specifically catalyzes the demethylation of mono- and di-methylated histone H3 lysine 4 through an FAD-dependent oxidative reaction. LSD1 is inappr...
Autores principales: | Alsaqer, Saqer F., Tashkandi, Mustafa M., Kartha, Vinay K., Yang, Ya-Ting, Alkheriji, Yazeed, Salama, Andrew, Varelas, Xaralabos, Kukuruzinska, Maria, Monti, Stefano, Bais, Manish V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650269/ https://www.ncbi.nlm.nih.gov/pubmed/29088714 http://dx.doi.org/10.18632/oncotarget.19637 |
Ejemplares similares
-
Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis
por: Alshenibr, Weam, et al.
Publicado: (2017) -
Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer
por: Kartha, Vinay K., et al.
Publicado: (2018) -
Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations
por: Dela Cruz, Ariana, et al.
Publicado: (2021) -
Targeting oral cancer epigenome via LSD1
por: Bais, Manish V.
Publicado: (2017) -
Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice
por: Tashkandi, Mustafa, et al.
Publicado: (2019)