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The downregulation of putative anticancer target BORIS/CTCFL in an addicted myeloid cancer cell line modulates the expression of multiple protein coding and ncRNA genes

The BORIS/CTCFL gene, is a testis-specific CTCF paralog frequently erroneously activated in cancer, although its exact role in cancer remains unclear. BORIS is both a transcription factor and an architectural chromatin protein. BORIS’ normal role is to establish a germline-like gene expression and r...

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Detalles Bibliográficos
Autores principales: Teplyakov, Evgeny, Wu, Qiongfang, Liu, Jian, Pugacheva, Elena M., Loukinov, Dmitry, Boukaba, Abdelhalim, Lobanenkov, Victor, Strunnikov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650274/
https://www.ncbi.nlm.nih.gov/pubmed/29088719
http://dx.doi.org/10.18632/oncotarget.20627

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