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Radioresistance of mesenchymal glioblastoma initiating cells correlates with patient outcome and is associated with activation of inflammatory program

Glioblastoma (GBM) still remains an incurable disease being radiotherapy (RT) the mainstay treatment. Glioblastoma intra-tumoral heterogeneity and Glioblastoma-Initiating Cells (GICs) challenge the design of effective therapies. We investigated GICs and non-GICs response to RT in a paired in-vitro m...

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Detalles Bibliográficos
Autores principales: Stanzani, Elisabetta, Martínez-Soler, Fina, Mateos, Teresa Martín, Vidal, Noemi, Villanueva, Alberto, Pujana, Miquel Angel, Serra-Musach, Jordi, de la Iglesia, Núria, Giménez-Bonafé, Pepita, Tortosa, Avelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650288/
https://www.ncbi.nlm.nih.gov/pubmed/29088733
http://dx.doi.org/10.18632/oncotarget.18363

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