Active evolution of memory B-cells specific to viral gH/gL/pUL128/130/131 pentameric complex in healthy subjects with silent human cytomegalovirus infection

Human cytomegalovirus (HCMV) can cause life-threatening infection in immunosuppressed patients, and in utero infection that may lead to birth defects. No vaccine is currently available. HCMV infection in healthy subjects is generally asymptomatic, and virus persists as latent infection for life. Hos...

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Autores principales: Xia, Lin, Tang, Aimin, Meng, Weixu, Freed, Daniel C., He, Linling, Wang, Dai, Li, Fengsheng, Li, Leike, Xiong, Wei, Gui, Xun, Schultz, Robbie D., Chen, Haotai, He, Xi, Swoyer, Ryan, Ha, Sha, Liu, Yaping, Morris, Charles D., Zhou, Yu, Wang, I-Ming, Zhao, Qinjian, Luo, Wenxin, Xia, Ningshao, Espeseth, Amy S., Hazuda, Daria J., Rupp, Richard E., Barrett, Alan D., Zhang, Ningyan, Zhu, Jiang, Fu, Tong-Ming, An, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650289/
https://www.ncbi.nlm.nih.gov/pubmed/29088734
http://dx.doi.org/10.18632/oncotarget.18359

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