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Long-term administration of ketamine induces erectile dysfunction by decreasing neuronal nitric oxide synthase on cavernous nerve and increasing corporal smooth muscle cell apoptosis in rats

We investigated and evaluated the mechanisms of erectile dysfunction (ED) in a rat model of long-term ketamine administration. Adult male Sprague-Dawley rats (n = 32) were divided into four groups: namely the control group receiving intraperitoneal injection of saline, 1-month, 2-month and 3-month g...

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Detalles Bibliográficos
Autores principales: Shang, Hung-Sheng, Wu, Yi-No, Liao, Chun-Hou, Chiueh, Tzong-Shi, Lin, Yuh-Feng, Chiang, Han-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650290/
https://www.ncbi.nlm.nih.gov/pubmed/29088735
http://dx.doi.org/10.18632/oncotarget.10727