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Long-term administration of ketamine induces erectile dysfunction by decreasing neuronal nitric oxide synthase on cavernous nerve and increasing corporal smooth muscle cell apoptosis in rats
We investigated and evaluated the mechanisms of erectile dysfunction (ED) in a rat model of long-term ketamine administration. Adult male Sprague-Dawley rats (n = 32) were divided into four groups: namely the control group receiving intraperitoneal injection of saline, 1-month, 2-month and 3-month g...
Autores principales: | Shang, Hung-Sheng, Wu, Yi-No, Liao, Chun-Hou, Chiueh, Tzong-Shi, Lin, Yuh-Feng, Chiang, Han-Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650290/ https://www.ncbi.nlm.nih.gov/pubmed/29088735 http://dx.doi.org/10.18632/oncotarget.10727 |
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