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Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity

Treatment of advanced head and neck squamous cell carcinoma (HNSCC) is plagued by low survival and high recurrence rates, despite multimodal therapies. Presently, cisplatin or cetuximab is used in combination with radiotherapy which has resulted in minor survival benefits but increased severe toxici...

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Detalles Bibliográficos
Autores principales: Dohmen, Amy J.C., Qiao, Xiaohang, Duursma, Anja, Wijdeven, Ruud H., Lieftink, Cor, Hageman, Floor, Morris, Ben, Halonen, Pasi, Vens, Conchita, van den Brekel, Michiel W.M., Ovaa, Huib, Neefjes, Jacques, Zuur, Charlotte L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650312/
https://www.ncbi.nlm.nih.gov/pubmed/29088757
http://dx.doi.org/10.18632/oncotarget.18034

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