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Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity
Treatment of advanced head and neck squamous cell carcinoma (HNSCC) is plagued by low survival and high recurrence rates, despite multimodal therapies. Presently, cisplatin or cetuximab is used in combination with radiotherapy which has resulted in minor survival benefits but increased severe toxici...
Autores principales: | Dohmen, Amy J.C., Qiao, Xiaohang, Duursma, Anja, Wijdeven, Ruud H., Lieftink, Cor, Hageman, Floor, Morris, Ben, Halonen, Pasi, Vens, Conchita, van den Brekel, Michiel W.M., Ovaa, Huib, Neefjes, Jacques, Zuur, Charlotte L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650312/ https://www.ncbi.nlm.nih.gov/pubmed/29088757 http://dx.doi.org/10.18632/oncotarget.18034 |
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