Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer

Cancer-Testis antigens (CTA) are immunogenic molecules with normal tissue expression restricted to testes but with aberrant expression in up to 30% of non-small cell lung cancers (NSCLCs). Regulation of CTA expression is mediated in part through promoter DNA methylation. Recently, immunotherapy has...

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Detalles Bibliográficos
Autores principales: Chüeh, Anderly C., Liew, Mun-Sem, Russell, Prudence A., Walkiewicz, Marzena, Jayachandran, Aparna, Starmans, Maud H.W., Boutros, Paul C., Wright, Gavin, Barnett, Stephen A, Mariadason, John M., John, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650321/
https://www.ncbi.nlm.nih.gov/pubmed/29088766
http://dx.doi.org/10.18632/oncotarget.18198

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