Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy

In contrast to the negligible expression of the immunomodulating protein CD70 in normal tissue, we have demonstrated constitutive overexpression of CD70 on tumor cells in a subset of primary non-small cell lung cancer (NSCLC) biopsies. This can be exploited by CD70-targeting antibody-dependent cellu...

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Detalles Bibliográficos
Autores principales: Jacobs, Julie, Deschoolmeester, Vanessa, Rolfo, Christian, Zwaenepoel, Karen, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, de Haard, Hans, Hermans, Christophe, Rottey, Sylvie, Vangestel, Christel, Lardon, Filip, Smits, Evelien, Pauwels, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650323/
https://www.ncbi.nlm.nih.gov/pubmed/29088768
http://dx.doi.org/10.18632/oncotarget.18202

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