ERG overexpression plus SLC45A3 (prostein) and PTEN expression loss: Strong association of the triple hit phenotype with an aggressive pathway of prostate cancer progression

TMPRSS2 and SLC45A3 rearrangements may coexist in the same tumor. ERG rearrangements and PTEN loss are concomitant events in prostate cancer (PrCa), and can cooperate in progression. We have reported that mRNA expression of TMPRSS2-ERG and SLC45A3-ERG rearrangements plus PTEN loss define an aggressi...

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Detalles Bibliográficos
Autores principales: Hernández-Llodrà, Silvia, Juanpere, Nuria, de Muga, Silvia, Lorenzo, Marta, Gil, Joan, Font-Tello, Alba, Agell, Laia, Albero-González, Raquel, Segalés, Laura, Merino, José, Serrano, Laia, Fumadó, Lluís, Cecchini, Lluís, Lloreta-Trull, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650326/
https://www.ncbi.nlm.nih.gov/pubmed/29088771
http://dx.doi.org/10.18632/oncotarget.18266

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