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Rs7911488 modified the efficacy of capecitabine-based therapy in colon cancer through altering miR-1307-3p and TYMS expression

Capecitabine is an orally administered prodrug of 5-fluouracil (5-FU) and is used in first-line treatment of metastatic colorectal cancer. Studies have demonstrated that polymorphisms in 5-FU related ADME genes are associated with the efficacy of capecitabine. However, the relationship between the p...

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Detalles Bibliográficos
Autores principales:	Chen, Qi, Mao, Yong, Meng, Fanyi, Wang, Lei, Zhang, Hongjian, Wang, Weipeng, Hua, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650342/ https://www.ncbi.nlm.nih.gov/pubmed/29088787 http://dx.doi.org/10.18632/oncotarget.19670

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