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Hypoxia negates hyperglycaemia-induced chemo-resistance in breast cancer cells: the role of insulin-like growth factor binding protein 2

BACKGROUND: Women who suffer from breast cancer and type II diabetes with associated hyperglycaemia respond less well to chemotherapy. We have shown that hyperglycaemia induces resistance to chemotherapy through upregulation of fatty acid synthase (FASN) in breast cancer cells and increased insulin-...

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Detalles Bibliográficos
Autores principales:	Al Qahtani, Athba, Holly, Jeff, Perks, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650368/ https://www.ncbi.nlm.nih.gov/pubmed/29088813 http://dx.doi.org/10.18632/oncotarget.20287

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