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Metformin inhibits esophageal squamous cell carcinoma-induced angiogenesis by suppressing JAK/STAT3 signaling pathway

Although it has been known that the tumor microenvironment affects angiogenesis, the precise mechanism remains unclear. In this study, we simulated the microenvironment of human esophageal squamous cell carcinoma (ESCC) by tumor conditioned medium (TCM) to assess the influence on normal endothelial...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Jin, Guoguo, Liu, Hangfan, Liu, Kangdong, Zhao, Jimin, Chen, Xinhuan, Wang, Dongyu, Bai, Ruihua, Li, Xiang, Jang, Yanan, Lu, Jing, Xing, Ying, Dong, Ziming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650371/
https://www.ncbi.nlm.nih.gov/pubmed/29088816
http://dx.doi.org/10.18632/oncotarget.20341