Cargando…

Obese donor mice splenocytes aggravated the pathogenesis of acute graft-versus-host disease via regulating differentiation of Tregs and CD4(+) T cell induced-type I inflammation

Acute graft-versus-host disease (aGVHD) remains one of the most severe complications in organ and bone marrow transplantation, leading to much morbidity and mortality. Obesity has been associated with increased risk of development of various inflammatory diseases. Here, we investigated the in vitro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zengyao, Gu, Jian, Zhu, Qin, Liu, Jing, Lu, Hao, Lu, Yunjie, Wang, Xuehao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650386/ https://www.ncbi.nlm.nih.gov/pubmed/29088831 http://dx.doi.org/10.18632/oncotarget.20425

Ejemplares similares

Rapamycin Regulates iTreg Function through CD39 and Runx1 Pathways
por: Lu, Yunjie, et al.
Publicado: (2014)

Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3(+) T Cell through Modulation of CD11b(+) Cell Function
por: Wu, Jianbo, et al.
Publicado: (2018)

Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation
por: Su, Xiuhua, et al.
Publicado: (2019)

Newly Found Peacekeeper: Potential of CD8+ Tregs for Graft-Versus-Host Disease
por: Wang, Weihao, et al.
Publicado: (2021)

Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses
por: Dai, Wujing, et al.
Publicado: (2016)

Donor Treg expansion by liposomal α‐galactosylceramide modulates Tfh cells and prevents sclerodermatous chronic graft‐versus‐host disease
por: Sugiura, Hiroyuki, et al.
Publicado: (2021)

Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice
por: Kosugi-Kanaya, Mizuha, et al.
Publicado: (2017)

CD8+CD103+ iTregs Inhibit Chronic Graft-versus-Host Disease with Lupus Nephritis by the Increased Expression of CD39
por: Zhang, Xiao, et al.
Publicado: (2019)

Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants
por: Wallace, Christopher Glenn, et al.
Publicado: (2012)

Tregs dysfunction aggravates postoperative cognitive impairment in aged mice
por: Zhou, Yile, et al.
Publicado: (2023)

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg)
por: Lu, Yunjie, et al.
Publicado: (2018)

THE INTERACTION OF DONOR AND HOST LYMPHOID CELLS IN THE PATHOGENESIS OF RENAL CORTICAL DESTRUCTION INDUCED BY A LOCAL GRAFT VERSUS HOST REACTION
por: Elkins, William L.
Publicado: (1966)

The Effect of Enzymatically Polymerised Polyphenols on CD4 Binding and Cytokine Production in Murine Splenocytes
por: Yamanaka, Daisuke, et al.
Publicado: (2012)

Protective effects of strawberry and mulberry fruit polysaccharides on inflammation and apoptosis in murine primary splenocytes
por: Liu, Chieh-Jung, et al.
Publicado: (2014)

Allogeneic Splenocyte Transfer and Lipopolysaccharide Inhalations Induce Differential T Cell Expansion and Lung Injury: A Novel Model of Pulmonary Graft-versus-Host Disease
por: Martinu, Tereza, et al.
Publicado: (2014)

Antibody response of mouse splenocytes using mixture of supernatants of thymocytes, adherent and non-adherent splenocytes: in-vitro immunization-II.
por: Kim, D., et al.
Publicado: (1990)

Difference between CD25(+)Tregs and Helios(+)Tregs in a murine model of allergic rhinitis
por: Wang, Yun-Xiu, et al.
Publicado: (2020)

Human CD39(hi) regulatory T cells present stronger stability and function under inflammatory conditions
por: Gu, Jian, et al.
Publicado: (2017)

Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses
por: Bolivar-Wagers, Sara, et al.
Publicado: (2022)

Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19(+)CD24(hi)CD27(+) Breg Cells
por: Li, Jinyang, et al.
Publicado: (2020)

Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape
por: Su, Xiuhua, et al.
Publicado: (2022)

Altered intestinal microbiome and epithelial damage aggravate intestinal graft-versus-host disease
por: Gao, Fei, et al.
Publicado: (2023)

Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease
por: Koyama, Motoko, et al.
Publicado: (2015)

Polyclonal Recipient nTregs Are Superior to Donor or Third-Party Tregs in the Induction of Transplantation Tolerance
por: Pilat, Nina, et al.
Publicado: (2015)

Murine gammaherpesvirus-68 expands, but does not activate, CD11b(+) gr-1(+) splenocytes in vivo
por: Nelson, Daniel A, et al.
Publicado: (2012)

Quantitative Analysis of Staphylococcus Enterotoxin A by Differential Expression of IFN-γ in Splenocyte and CD4(+) T-Cells
por: Rasooly, Reuven, et al.
Publicado: (2014)

Critical role of FPR1 in splenocyte migration into brain to worsen inflammation and ischemic brain injury in mice
por: Li, Jun, et al.
Publicado: (2022)

Circulating CD4(+) Treg, CD8(+) Treg, and CD3(+) γδ T Cell Subpopulations in Ovarian Cancer
por: Li, Rong, et al.
Publicado: (2023)

Anti-CD137 mAb Deletes Both Donor CD4(+) and CD8(+) T Cells in Acute Graft-versus-host Disease
por: Kim, Juyang, et al.
Publicado: (2011)

Metformin alleviates allergic airway inflammation and increases Treg cells in obese asthma
por: Guo, Yimin, et al.
Publicado: (2021)

Atrazine-induced apoptosis of splenocytes in BALB/C mice
por: Zhang, Xiaofeng, et al.
Publicado: (2011)

Transient B-Cell Depletion Combined With Apoptotic Donor Splenocytes Induces Xeno-Specific T- and B-Cell Tolerance to Islet Xenografts
por: Wang, Shusen, et al.
Publicado: (2013)

ECDI‐fixed donor splenocytes prolong skin allograft survival by promoting M2 macrophage polarization and inducing regulatory T cells
por: Zhou, Bo, et al.
Publicado: (2019)

Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis
por: Scheffel, Matthew J., et al.
Publicado: (2017)

Editorial: Pathogenesis and Therapy of Graft-versus-Host Disease
por: Betts, Brian C., et al.
Publicado: (2019)

In Vivo Dynamical Interactions between CD4 Tregs, CD8 Tregs and CD4(+)CD25(−) Cells in Mice
por: Arazi, Arnon, et al.
Publicado: (2009)

Strategies for Enhancing and Preserving Anti-leukemia Effects Without Aggravating Graft-Versus-Host Disease
por: Chang, Ying-Jun, et al.
Publicado: (2018)

Use of Tregs as a cell‐based therapy via CD39 for benign prostate hyperplasia with inflammation
por: Jin, Xi, et al.
Publicado: (2020)

Human umbilical cord-derived mesenchymal stem cells alleviate insulin resistance in diet-induced obese mice via an interaction with splenocytes
por: Xue, Jing, et al.
Publicado: (2022)

Aggravation of Allergic Airway Inflammation by Cigarette Smoke in Mice Is CD44-Dependent
por: Kumar, Smitha, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_p2ft80hora15g6f062vb40ajk6