A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population

Pulmonary arterial hypertension (PAH) is a lethal disease that often affects the young. Although Bone Morphogenetic Protein Receptor Type 2 gene (BMPR2) mutations are related with idiopathic and heritable PAH, the low penetrance and variable expressivity in PAH suggest the existence of other genetic...

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Detalles Bibliográficos
Autores principales: Kimura, Mai, Tamura, Yuichi, Guignabert, Christophe, Takei, Makoto, Kosaki, Kenjiro, Tanabe, Nobuhiro, Tatsumi, Koichiro, Saji, Tsutomu, Satoh, Toru, Kataoka, Masaharu, Kamitsuji, Shigeo, Kamatani, Naoyuki, Thuillet, Raphaël, Tu, Ly, Humbert, Marc, Fukuda, Keiichi, Sano, Motoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650389/
https://www.ncbi.nlm.nih.gov/pubmed/29088834
http://dx.doi.org/10.18632/oncotarget.20459

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