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Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone
Therapies that target cancer cells may have unexpected effects on the tumor microenvironment that affects therapy outcomes or render therapy resistance. Prostate cancer (PCa) bone metastasis is uniquely associated with osteoblastic bone lesions and treatment with cabozantinib, a VEGFR-2 and MET inhi...
Autores principales: | Yu, Kai-Jie, Li, Jeffrey K., Lee, Yu-Chen, Yu, Guoyu, Lin, Song-Chang, Pan, Tianhong, Satcher, Robert L., Titus, Mark A., Yu-Lee, Li-Yuan, Weng, Wen Hui, Gallick, Gary E., Lin, Sue-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650395/ https://www.ncbi.nlm.nih.gov/pubmed/29088840 http://dx.doi.org/10.18632/oncotarget.20489 |
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