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Nicotine suppresses apoptosis by regulating α7nAChR/Prx1 axis in oral precancerous lesions
Nicotine, a tumor promoter in tobacco, can increase Peroxiredoxin (Prx1) and nicotinic acetylcholine receptors (nAChRs) in oral squamous cell carcinoma (OSCC). In the present study, we investigate the effects of nicotine in oral precancerous lesions focusing on apoptosis and nAChR/Prx1 signaling. We...
Autores principales: | Wang, Chunxiao, Niu, Wenwen, Chen, Hui, Shi, Ni, He, Dian, Zhang, Min, Ge, Lihua, Tian, Zhenchuan, Qi, Moci, Chen, Tong, Tang, Xiaofei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650400/ https://www.ncbi.nlm.nih.gov/pubmed/29088845 http://dx.doi.org/10.18632/oncotarget.20506 |
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