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Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression
Tuning the solubility of fuzzy polymer microgels by external triggers, such as temperature or pH, provides a unique mechanism for controlling the porosity and size of colloidal particles on the nanoscale. As a consequence, these smart microgel particles are being considered for applications ranging...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650484/ https://www.ncbi.nlm.nih.gov/pubmed/29062888 http://dx.doi.org/10.1126/sciadv.1700969 |
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author | Conley, Gaurasundar M. Aebischer, Philippe Nöjd, Sofi Schurtenberger, Peter Scheffold, Frank |
author_facet | Conley, Gaurasundar M. Aebischer, Philippe Nöjd, Sofi Schurtenberger, Peter Scheffold, Frank |
author_sort | Conley, Gaurasundar M. |
collection | PubMed |
description | Tuning the solubility of fuzzy polymer microgels by external triggers, such as temperature or pH, provides a unique mechanism for controlling the porosity and size of colloidal particles on the nanoscale. As a consequence, these smart microgel particles are being considered for applications ranging from viscosity modifiers and sensing to drug delivery and as models for the glass and the jamming transition. Despite their widespread use, little is known about how these soft particles adapt their shape and size under strong mechanical compression. We use a combination of precise labeling protocols and two-color superresolution microscopy to unravel the behavior of tracer microgels inside densely packed soft solids. We find that interpenetration and shape deformation are dominant until, in the highly overpacked state, this mechanism saturates and the only remaining way to further densify the system is by isotropic compression. |
format | Online Article Text |
id | pubmed-5650484 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-56504842017-10-23 Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression Conley, Gaurasundar M. Aebischer, Philippe Nöjd, Sofi Schurtenberger, Peter Scheffold, Frank Sci Adv Research Articles Tuning the solubility of fuzzy polymer microgels by external triggers, such as temperature or pH, provides a unique mechanism for controlling the porosity and size of colloidal particles on the nanoscale. As a consequence, these smart microgel particles are being considered for applications ranging from viscosity modifiers and sensing to drug delivery and as models for the glass and the jamming transition. Despite their widespread use, little is known about how these soft particles adapt their shape and size under strong mechanical compression. We use a combination of precise labeling protocols and two-color superresolution microscopy to unravel the behavior of tracer microgels inside densely packed soft solids. We find that interpenetration and shape deformation are dominant until, in the highly overpacked state, this mechanism saturates and the only remaining way to further densify the system is by isotropic compression. American Association for the Advancement of Science 2017-10-20 /pmc/articles/PMC5650484/ /pubmed/29062888 http://dx.doi.org/10.1126/sciadv.1700969 Text en Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Conley, Gaurasundar M. Aebischer, Philippe Nöjd, Sofi Schurtenberger, Peter Scheffold, Frank Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression |
title | Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression |
title_full | Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression |
title_fullStr | Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression |
title_full_unstemmed | Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression |
title_short | Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression |
title_sort | jamming and overpacking fuzzy microgels: deformation, interpenetration, and compression |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650484/ https://www.ncbi.nlm.nih.gov/pubmed/29062888 http://dx.doi.org/10.1126/sciadv.1700969 |
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